Annotation

Epilepsy is the most chronic neurological disorder affecting 40 million people worldwide. Approximately one-third of people with epilepsy don't respond to available anti-seizure therapy. The effective cure for epilepsy still represents an unmet need. The development of innovative therapies is the priority of contemporary epilepsy research.
To achieve this goal, the professionals working in epilepsy research need to understand the molecular, structural, and functional mechanisms that underlie the pathogenesis of epilepsy and seizures, combined with the understanding of the emerging technologies that can be used to study and treat epilepsy.
In response to this need, we have brought together a faculty of epilepsy specialists to develop an international course that will be delivered online. This 75-hour online course introduces the participants to the basic principles of epilepsies. The topics cover molecular, cellular, and network mechanisms involved in the pathogenesis of epilepsies.

Results of learning

After the course, the participant will be able to:
•Explain the cellular, network, molecular, and metabolic processes that characterize the chronic epileptic tissue, epileptic neurons, and pathological activity between seizures and seizures.
•Report how the mechanisms vary in various forms of epilepsy, ranging from focal epilepsy to generalized and epileptic encephalopathies.
•Characterize the mechanisms that are responsible for the development of epilepsy.
•Describe how various types of lesions lead to epilepsy and seizures.
•Explain how brain development and brain aging affect the brain's susceptibility to develop epilepsy and the underlying mechanism.
•Characterize the basic principles of various research techniques and justify what information they provide to gain insight into the pathophysiological mechanisms of epilepsy.
•Explain how understanding the pathophysiological mechanisms and pathogenesis of epilepsy is relevant for understanding the effect of currently available anti-seizure medication and developing new diagnostic techniques and epilepsy therapy.
•Critically evaluate the current challenges of epilepsy research.
•Name the needs of people with epilepsy and their expectations from the research.